an issue of critical importance for proteomics analysis of complex biological and clinical samples for discoery of biomarkers is the need for reduction of tissue sample complexity prior to ms analysis 對復(fù)雜的生物學(xué)與臨床樣本進(jìn)行蛋白質(zhì)組學(xué)分析以期發(fā)現(xiàn)生物標(biāo)志物的一個關(guān)鍵問題是在進(jìn)行ms分析前需要弱化組織樣品的復(fù)雜程度。
3 . the variation of the number of the principle components, shape, physical meaning and the explainablity with the change of calibration data and the sample complexity is systematically studied for the first time 首次系統(tǒng)研究了隨著樣品成份復(fù)雜性的變化以及光譜數(shù)據(jù)預(yù)處理方法和波長區(qū)域的不同,主成分的個數(shù)、意義及其可解釋性的變化情況。